Chlorhexidine and green tea extract reduce dentin erosion and abrasion in situ

Chlorhexidine and green tea extract reduce dentin erosion and abrasion in situ

Author: Ana Carolina Magalhães and Annette Wiegand and Daniela Rios and Angélica Hannas and Thomas Attin and Marília Afonso Rabelo Buzalaf

Objectives This in situ/ex vivo study aimed to analyse the impact of possible MMP-inhibitors (chlorhexidine and green tea extract) on dentin wear induced by erosion or erosion plus abrasion. Methods Twelve volunteers took part in this cross-over and double-blind study performed in 4 phases of each 5 days. Bovine dentin samples were worn in palatal appliances and subjected to extraoral erosion (4 times/day, Coca-Cola, 5 min) or erosion plus abrasion (2 times/day, fluoride-free toothpaste and electrical toothbrush, 15 s/sample). Immediately after each erosion, the appliances were reinserted in the mouth and the oral cavity was rinsed for 60 s with: 250 ppm F solution (SnF2/AmF, pH 4.5, Meridol-Gaba, Switzerland), 0.12% chlorhexidine digluconate (0.06% chlorhexidine, pH 6.0, Periogard-Colgate, Brazil), 0.61% green tea extract solution (OM24®, 100% Camellia Sinensis leaf extract, catechin concentration: 30 ± 3%, pH 7.0, Omnimedica, Switzerland) or deionized water (pH 6.0, control). Dentin loss was assessed by profilometry (μm). The data were analysed by two-way repeated measures ANOVA and Bonferroni post hoc test. Results There was a significant difference between the conditions (Ero × Ero + Abr, p < 0.001) and among the solutions (p < 0.001). All solutions (F: 1.42 ± 0.34; 1.73 ± 0.50, chlorhexidine: 1.15 ± 0.26; 1.59 ± 0.32, green tea: 1.06 ± 0.30; 1.54 ± 0.55) significantly reduced the dentin wear when compared to control (2.00 ± 0.55; 2.41 ± 0.83) for both conditions. There were not significant differences among green tea extract, chlorhexidine and F solutions. Conclusions Thus, the possible MMP-inhibitors tested in this study seem to be a promising preventive measure to reduce dentin erosion-abrasion, but their mechanism of action needs to be investigated in further studies.


Get the whole article here

Shipping Icon Free Shipping + Free Returns
Subscription Details Icon
We stand behind our teas and teaware, and want you to be not just satisfied with them, but thrilled. If for any reason you're not, just let us know and we'll do our best to make it right.

{property.value} {property.value} {property.value} Include jar: {property.value}
You definitely need tools!
Perfect coldbrew everytime
The ideal way to store your matcha
The ideal way to store your matcha