M.489 The effect of green tea on lipid profile and oxidative stress
Author: S. Coimbra and P. Rocha-Pereira and I. Rebelo and S. Rocha and A. Santos-Silva and E.M.B. Castro
Several studies suggest a protective effect of green tea prepared with leafs of Camellia sinensis for CVD. The interest of the green tea is due to its high content in catechins. Our aim was to evaluate the effect of green tea on some risk factors for CVD. A sample of 34 Portuguese individuals was used. We evaluated the total cholesterol, HDLc, LDLc, triglycerides, lipoprotein (a), apolipoprotein A-I and B, total antioxidant status, lipid peroxidation products, oxidative changes in erythrocyte membrane and the P-selectin levels. The analyses were performed at the beginning, after 3 weeks drinking 1 liter of water daily, and after 4 weeks drinking 1 liter of green tea daily. The tea was prepared everyday in the same conditions. We found no dilution effect on the analyzed parameters. After ingestion of green tea, we found a significant reduction in total cholesterol, LDLc, and apolipoprotein B; an increase in HDLc and apolipoprotein A-I; a decrease in lipid peroxidation and a significant reduction in the oxidative stress within the erythrocyte. We found also an increase in the antioxidant capacity and a decrease in P-selectin levels. Our resuts suggest that green tea has a beneficial effect, protecting for CVD, by improving the lipid profile and the oxidative stress.
