Relation between Green Tea Consumption and the Severity of Coronary Atherosclerosis among Japanese Men and Women
Author: Shizuka Sasazuki and Hiroko Kodama and Kouichi Yoshimasu and Ying Liu and Masakazu Washio and Keitaro Tanaka and Shoji Tokunaga and Suminori Kono and Hidekazu Arai and Yoshitaka Doi and Tomoki Kawano and Osamu Nakagaki and Kazuyuki Takada and Samon Koyanagi and Koji Hiyamuta and Takanobu Nii and Kazuyuki Shirai and Munehito Ideishi and Kikuo Arakawa and Masahiro Mohri and Akira Takeshita
PURPOSE: To examine the relation between green tea consumption and arteriographically determined coronary atherosclerosis. METHODS: Study subjects were 512 patients (302 men and 210 women) aged 30 years or older who underwent coronary arteriography for the first time at four hospitals in Fukuoka City or one hospital in an adjacent city between September 1996 and August 1997. Lifestyle characteristics including green tea consumption were ascertained before arteriography by a questionnaire supported with interview. RESULTS: 117 men (38.7%) and 50 women (23.8%) had significant stenosis of one or more coronary arteries. Green tea consumption tended to be inversely associated with coronary atherosclerosis in men, but not in women. An evident, protective association between green tea and coronary atherosclerosis was observed in a subgroup of 262 men excluding those under dietary or drug treatment for diabetes mellitus. In this subgroup, after adjustment for traditional coronary risk factors and coffee, odds ratios of significant stenosis for consumption of 2–3 cups and 4 or more cups per day were 0.5 (95% confidence interval 0.2–1.2) and 0.4 (0.2–0.9), respectively, as compared with a consumption of one cup per day or less. CONCLUSIONS: The results indicate that green tea may be protective against coronary atherosclerosis at least in men.