Research Database

The only comprehensive database for clinical and medical research papers on the healthy benefits of matcha/green tea

Recent Research Papers on
mental-health

Memory deficits and oxidative stress in cerebral ischemia–reperfusion: Neuroprotective role of physical exercise and green tea supplementation

Author: Helen L. Schimidt and Aline Vieira and Caroline Altermann and Alexandre Martins and Priscila Sosa and Francielli W. Santos and Pâmela B. Mello-Carpes and Ivan Izquierdo and Felipe P. Carpes

Ischemic stroke is a major cause of morbidity and mortality all over the world. Among impairments observed in survivors there is a significant cognitive learning and memory deficit. Neuroprotective strategies are being investigated to minimize such deficits after an ischemia event. Here we investigated the neuroprotective potential of physical exercise and green tea in an animal model of ischemia–reperfusion. Eighty male rats were divided in 8 groups and submitted to either transient brain ischemia–reperfusion or a sham surgery after 8 weeks of physical exercise and/or green tea supplementation. Ischemia–reperfusion was performed by bilateral occlusion of the common carotid arteries during 30 min. Later, their memory was evaluated in an aversive and in a non-aversive task, and hippocampus and prefrontal cortex were removed for biochemical analyses of possible oxidative stress effects. Ischemia–reperfusion impaired learning and memory. Reactive oxygen species were increased in the hippocampus and prefrontal cortex. Eight weeks of physical exercise and/or green tea supplementation before the ischemia–reperfusion event showed a neuroprotective effect; both treatments in separate or together reduced the cognitive deficits and were able to maintain the functional levels of antioxidant enzymes and glutathione.

 

 

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Other Popular Research Topics

Cognitive Function

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Heart Health

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According to Harvard Medical School, “lowering your risk of cardiovascular disease may be as easy as drinking green tea. Studies suggest this light, aromatic tea may lower LDL cholesterol and triglycerides, which may be responsible for the tea's association with reduced risk of death from heart disease and stroke.”

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Cancer Prevention

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Matcha/green tea has for many centuries been regarded as an essential part of good health in Japan and China. Many believe it can help reduce the risk of cancer, and a growing body of evidence backs this up.

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Immunity

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A recent study in the journal Proceedings of the National Academy of Sciences concluded that drinking matcha daily greatly enhanced the overall response of the immune system. The exceedingly high levels of antioxidants in matcha mainly take the form of polyphenols, catechins, and flavonoids, each of which aids the body’s defense in its daily struggles against free radicals that come from the pollution in your air, water and foods.

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