Theanine-induced Reduction of Brain Serotonin Concentration in Rats

Theanine-induced Reduction of Brain Serotonin Concentration in Rats

Author: Hidehiko YOKOGOSHI, and Mikiko MOCHIZUKI, and Kotomi SAITOH

Following the administration of theanine, the brain tryptophan content significantly increased or tended to increase, but the contents of serotonin and 5-hydroxyindole acetic acid (5HIAA) decreased. The use of inhibitors of serotonin metabolism enable us to speculate that theanine reduced serotonin synthesis and also increased serotonin degradation in the brain.

 

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